Dr. Josh Denny, chief executive officer of the All of Us Research Program at the National Institutes of Health, will step down on October 31, 2026, to accept a leadership position at the University of Chicago, NIH Director Jay Bhattacharya announced.
Denny joined NIH in 2020 to lead the program, which he helped shape from conception through his role on the Advisory Committee to the NIH Director. Under his leadership, All of Us grew to include nearly 900,000 participant partners and became what NIH described as the world's largest integrated genomic and electronic health record dataset.
The program returned individual genetic results to over 277,000 participants, including providing more than 5,620 participants with potentially life-saving insights across more than 59 actionable genes and over 158,000 participants with results that inform medication response.
Dr. Stephanie Devaney, the program's Chief Operating Officer, will serve as Acting Chief Executive Officer. Devaney has been with All of Us since its inception. NIH will conduct a national search for the next permanent CEO.
During the transition, the program will continue active enrollment nationwide alongside expansion into pediatric and family recruitment. More than 25,000 registered researchers worldwide will maintain access to the Researcher Workbench, which now includes data from the Environmental Influences on Child Health Outcomes cohort. Participant data remains under high federal security and privacy protections.